The authors used a bottom‑up thermodynamic modelling framework to investigate how plants decode calcium signals, starting from Ca2+ binding to EF‑hand proteins and extending to higher‑order decoding modules. They identified six universal Ca2+-decoding modules that can explain variations in calcium sensitivity among kinases and provide a theoretical basis for interpreting calcium signal amplitude and frequency in plant cells.
Impaired methyl recycling induces substantial shifts in sulfur utilization in Arabidopsis
Authors: Tremblay, B. J.-M., Adeel, S. A., Saechao, M., Dong, Y., Andrianasolo, E., Steele, J. M., Traa, A., Yogadasan, N., Waduwara-Jayabahu, I., Katzenback, B. A., Hell, R., Wirtz, M., Moffatt, B. A.
Reduced activity of methylthioadenosine (MTA) nucleosidase causes MTA over‑accumulation in reproductive tissues, leading to lowered cysteine, methionine, and S‑adenosylmethionine levels and altered sulfur and energy metabolism. These metabolic disturbances trigger misregulation of cell‑cycle progression, widespread down‑regulation of developmental genes, and genome‑wide changes in DNA methylation patterns, highlighting the extensive role of MTA recycling in plant growth and methyl‑index maintenance.