Comparative gene regulatory network mapping of Brassicaceae members with differential drought tolerance
Authors: Pandiarajan, R., Lin, C.-W., Sauer, M., Rothballer, S. T., Marin-de la Rosa, N., Schwehn, P., Papadopoulou, E., Mairhormann, B., Falter-Braun, P.
Category: Plant Biology
Model Organism: Multi-species
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The study mapped drought‑responsive gene regulatory networks in Arabidopsis thaliana, its tolerant relative Arabidopsis lyrata, and Eutrema salsugineum using yeast one‑hybrid screens of orthologous promoters, revealing higher network connectivity and specific TF‑promoter interactions in the tolerant species. Notable findings include an Esa‑specific expansion of bZIP interactions, differential ABA‑signalling edges, and the identification of ASIL2 as a novel stress‑responsive factor, providing a comparative framework for improving crop drought tolerance.