The study investigated melatonin priming on methylglyoxal detoxification and autophagy during PEG‑induced drought stress in seed germination of drought‑sensitive (L‑799) and tolerant (Suraj) upland cotton. Melatonin increased endogenous melatonin, reduced MGO and AGEs, up‑regulated glyoxalase enzymes and autophagy markers, and improved cell viability in the sensitive variety, while the tolerant variety showed limited response.
Lack of AtMC1 catalytic activity triggers autoimmunity dependent on NLR stability
Authors: Salguero-Linares, J., Armengot, L., Ayet, J., Ruiz-Solani, N., Saile, S., Salas-Gomez, M., Fernandez, E., Denolf, L., Navarrete, F., Krumbach, J., Kaiser, M., Stael, S., Van Breusegem, F., Gevaert, K., Kaschani, F., petersen, m., El Kasmi, F., Valls, M., Coll, N. S.
The study demonstrates that loss of Arabidopsis metacaspase 1 (AtMC1) triggers autoimmunity reliant on downstream NLR and PRR signaling, and that overexpressing a catalytically dead AtMC1 exacerbates this effect. Overexpression of the E3 ligase SNIPER1 restores normal immunity, suggesting that AtMC1 regulates NLR protein turnover, possibly via autophagic degradation of the inactive protein.