Primary metabolism determines the outcome of salicylic acid-mediated immune induction
Authors: Zhang, Q., Xie, Y., Karapetyan, S., Wang, J., Mwimba, M., Yoo, H., Dong, X.
Date: 2025-10-14 · Version: 1
DOI: 10.1101/2025.10.13.682132 Category: Plant Biology
Model Organism: General
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The study identified twenty survival of SA-induced death (ssd) mutants that are defective in starch, glucose, nitrate metabolism, and circadian regulation, leading to excessive carbohydrate accumulation and susceptibility to salicylic acid (SA)-induced death in prolonged darkness. Glucose application rescues SA‑treated plants by antagonizing oxidative stress and restoring metabolic balance, as revealed by transcriptomic analyses that link SA‑induced cell death to effector‑triggered immunity pathways.
salicylic acid circadian regulation starch and glucose metabolism oxidative stress glucose rescue