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A Key Role for S-Nitrosylation in Immune Regulation and Development in the Liverwort Marchantia polymorpha

Authors: Goodrich, J.

Date: 2025-09-30 · Version: 1
DOI: 10.1101/2025.09.29.679193

Category: Plant Biology

Model Organism: Marchantia polymorpha

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The study characterizes the single-copy S-nitrosoglutathione reductase 1 (MpGSNOR1) in the liverwort Marchantia polymorpha, showing that loss-of-function mutants generated via CRISPR/Cas9 exhibit marked morphological defects and compromised SNO homeostasis and immune responses. These findings indicate that GSNOR-mediated regulation of S‑nitrosylation is an ancient mechanism linking development and immunity in early land plants.

Nitric oxide S-nitrosylation GSNOR Marchantia polymorpha plant immunity