Loss of tomato geranylgeranyl diphosphate synthase 2 increases monoterpenoid levels and enhances immune responses to bacterial infection
Authors: Perez-Perez, J., Ezquerro, M., Lim, S., Ha, S.-H. S. H., Lopez-Gresa, M. P., Rodriguez-Concepcion, M., Lison, P.
Date: 2025-03-26 · Version: 1
DOI: 10.1101/2025.03.24.644926 Category: Plant Biology
Model Organism: Solanum lycopersicum
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The study investigated three plastidial GGPP synthase isoforms in tomato, focusing on SlG2’s role in volatile isoprenoid production and disease resistance. CRISPR-edited slg2 mutants exhibited elevated geranyl diphosphate-derived monoterpenes and higher salicylic acid levels, leading to increased resistance against Pseudomonas syringae infection. The authors propose that SlG2 modulates GPP synthesis by competing for heterodimerization with SSU-I proteins.
GGPP synthase SlG2 monoterpenes salicylic acid Pseudomonas syringae infection